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Myostatin, human recombinant protein
GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O14793 |
|---|---|
| Calculated MW | 24.8 kDa |
| Gene ID | 2660 |
|---|---|
| Gene Symbol | GDF8 |
| Other Names | GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥98% |
| Assay2&Purity2 | HPLC; ≥98% |
| Recombinant | Yes |
| Results | <20 ng/ml |
| Target/Specificity | Myostatin |
| Application Notes | It is recommended to reconstitute the lyophilized human Myostatin in sterile 20 mM acetic acid to a concentration of 0.1 to 1.0 mg/ml. This solution can then be diluted into other aqueous buffers. |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and lyophilized with no additives |
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Provided below are standard protocols that you may find useful for product applications.
Background
Myostatin, also known as Growth Differentiation Factor-8 (GDF-8), belongs to the TGF-β superfamily. Along with other members of the TGF-β family, Myostatin plays a crucial role as a regulator for embryonic development and tissue homeostasis in adult animals. Early studies show that Myostatin has the ability to halt muscle growth. New research has further suggested that Myostatin may also be involved in reducing and preventing adiposity and type-2 diabetes. Human Myostatin is a homodimeric protein with each subunit containing 109 amino acid residues with a total molecular weight of 24.8 kDa.
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