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Myostatin Proform, human recombinant protein

GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy,

Product info
Primary Accession O14793
Calculated MW 27.8 kDa
Additional Info
Gene ID 2660
Gene Symbol MSTN
Other Names GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy,
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC; ≥98%
Recombinant Yes
Target/Specificity Myostatin
Application Notes Reconstitute in H₂O to a concentration of 0.1 to 1.0 mg/ml. This solution can then be diluted into other aqueous buffers
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized with no additives
Citations (0)

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Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in Myostatin knockout mice. Recombinant Human Myostatin Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues


McPherron A.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:12457-12461(1997).
Gonzalez-Cadavid N.F.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:14938-14943(1998).
Saunders M.A.,et al.Am. J. Hum. Genet. 79:1089-1097(2006).
Hill J.J.,et al.Mol. Endocrinol. 17:1144-1154(2003).
Schuelke M.,et al.N. Engl. J. Med. 350:2682-2688(2004).

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$ 190.00
$ 5,450.00
Cat# PBV10334r-10
Availability: 5-7days
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