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RELM-alpha, murine recombinant protein
Resistin-like α, RELMα, Cysteine-rich secreted protein FIZZ1, Parasite-induced macrophage novel gene
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9EP95 |
|---|---|
| Calculated MW | 10.0 kDa |
| Gene ID | 57262 |
|---|---|
| Gene Symbol | RETNA |
| Other Names | Resistin-like α, RELMα, Cysteine-rich secreted protein FIZZ1, Parasite-induced macrophage novel gene 1 protein, Cysteine-rich secreted protein A12-γ, RELM-a |
| Gene Source | Mouse |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥98% |
| Assay2&Purity2 | HPLC; ≥98% |
| Recombinant | Yes |
| Target/Specificity | RELM-alpha |
| Application Notes | Reconstitute in H₂O to a concentration of 0.1-1 µg/ µl. The solution can then be diluted into other aqueous buffers |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and lyophilized from 10 mM Tris, pH 7.5 + 25 mM NaCl. |
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Provided below are standard protocols that you may find useful for product applications.
Background
RELM-α belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-α and Resistin are secreted exclusively by adipocytes while RELM-β is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-α re still unknown. Recombinant murine RELM-α is a 10.0 kDa monomeric protein containing 88 amino acid residues.
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