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Galectin-7, human recombinant protein
Galactein 7, Galectin7, Gal-7, HKL-14, PI7, p53-induced gene 1 protein
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P47929 |
|---|---|
| Calculated MW | 15.4 kDa |
| Gene ID | 3963 |
|---|---|
| Gene Symbol | LGALS7 |
| Other Names | Galactein 7, Galectin7, Gal-7, HKL-14, PI7, p53-induced gene 1 protein |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥98% |
| Assay2&Purity2 | HPLC; ≥98% |
| Recombinant | Yes |
| Results | 1-7 mg/ml. |
| Target/Specificity | Galectin-7 |
| Application Notes | Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and lyophilized with no additives |
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Provided below are standard protocols that you may find useful for product applications.
Background
Galectin-7 belongs to growing family of evolutionary conserved animal lectins. Galectins consists of β-galactoside binding lectins that contain homologous carbohydrate recognition domains (CRDs). Galectin has the ability to induce apoptosis of activated T-cells and T-leukaemia cell lines. Other activities include cell differentiation and inhibition activity of CD45 protein phosphatase activity. Galectin also binds β-galactoside as well as CD45, CD3 and CD4. Recombinant Human Galectin-7 is a 15.4 kDa protein consisting of 136 amino acid residues
References
Madsen P.,et al.J. Biol. Chem. 270:5823-5829(1995).
Magnaldo T.,et al.Dev. Biol. 168:259-271(1995).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Kuwabara I.,et al.J. Biol. Chem. 277:3487-3497(2002).
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