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PTH, human recombinant protein

Parathyrin, PTH, Parathormone

     
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Product info
Primary Accession P01270
Calculated MW 9.0 kDa
Additional Info
Gene ID 5741
Gene Symbol PTH
Other Names Parathyrin, PTH, Parathormone
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE;
Assay2&Purity2 HPLC; ≥98%
Recombinant Yes
Target/Specificity PTH
Application Notes Reconstitute in H₂O to a concentration of 0.1-1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized powder
Citations (0)
citation

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Background

Parathyroid Hormone (PTH) is the most important endocrine regulator of calcium and phosphorus concentration in extraCellular fluid. This hormone is secreted from cells of the parathyroid glands and targets cells in bone and kidney. Like other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intraCellular processing, the mature hormone is packaged within the Golgi into secretary vesicles and secreted into blood by exocytosis. Recombinant human PTH is a 9 kDa protein consisting of 84 amino acid residues.

References

Hendy G.N.,et al.Proc. Natl. Acad. Sci. U.S.A. 78:7365-7369(1981).
Vasicek T.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:2127-2131(1983).
Karaplis A.C.,et al.J. Biol. Chem. 270:1629-1635(1995).
Jacobs J.W.,et al.Nature 249:155-157(1974).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).

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Discontinued
Cat# PBV10344r-1
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