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RELM-beta, human recombinant protein
Resistin-like β, RELM β, Cysteine-rich secreted protein FIZZ2, Colon and small intestine-specific cy
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BQ08 |
|---|---|
| Calculated MW | 11.0 kDa |
| Gene ID | 84666 |
|---|---|
| Gene Symbol | RETNB |
| Other Names | Resistin-like β, RELM β, Cysteine-rich secreted protein FIZZ2, Colon and small intestine-specific cysteine-rich protein, Cysteine-rich secreted protein A12-α-like 1, Colon carcinoma-related gene protein, RELM-b, XCP2, HXCP2 |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; ≥95% |
| Recombinant | Yes |
| Application Notes | Reconstitute to 1 mg/ml with sterilized dH₂O. Pipet to dissolve the protein pellet completely. |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and lyophilized with no additives |
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Provided below are standard protocols that you may find useful for product applications.
Background
Human RELM β (Resistin-like molecule β/FIZZ2) is a new member to the family of adipocyte secreted proteins called adipocytokines. This family includes the RELM α, RELM β and Resistin molecules. Interestingly, RELM β and Resistin share similar characteristics such as an additional cysteine residue within the variable N-terminal region and are both homodimeric proteins. However, the RELM β is expressed only in the gastrointestinal track; especially the colon, while the Resistin and RELM β are secreted exclusively by adipocytes. Currently, the biological function of these proteins, as well as their molecular targets is largely unknown. Recombinant Human RELM β is a disulfide-linked homodimer with a total molecular weight of 11.0 kDa, consisting of 90 amino acid residue chains.
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