Prolactin, human recombinant protein
Mammotropin, Luterotropic hormone, Lutetropin, Prlr, PRL, luteotropic hormone, LTH, PRLR, PRL-R, PRL
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P01236 |
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Calculated MW | 23.3 kDa |
Gene ID | 5617 |
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Gene Symbol | PRL |
Other Names | Mammotropin, Luterotropic hormone, Lutetropin, Prlr, PRL, luteotropic hormone, LTH, PRLR, PRL-R, PRL R |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥95% |
Assay2&Purity2 | HPLC; ≥95% |
Recombinant | Yes |
Results | <0.065 ng/ml |
Application Notes | Reconstitute in H₂O to a concentration of 1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. |
Format | Lyophilized protein |
Storage | -20°C; Sterile filtered and lyophilized from 10 mM Sodium Phosphate, pH 8.0 + 50 mM NaCl. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Prolactin (also known as mammotrophin, luterotropic hormone, and lutetropin) is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, Prolactin plays an immune-regulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant human Prolactin is a 23 kDa globular protein containing 200 amino acid residues.
References
Cooke N.E.,et al.J. Biol. Chem. 256:4007-4016(1981).
Truong A.T.,et al.EMBO J. 3:429-437(1984).
Hiraoka Y.,et al.Mol. Cell. Endocrinol. 75:71-80(1991).
Takahashi H.,et al.J. Biochem. 95:1491-1499(1984).
Shaw-Bruha C.M.,et al.Breast Cancer Res. Treat. 44:243-253(1997).
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