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Apolipoprotein CIII, Human Plasma recombinant protein
Apolipoprotein CIII
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P02656 |
|---|---|
| Calculated MW | 8.750 kDa |
| Gene ID | 345 |
|---|---|
| Gene Symbol | APOC3 |
| Other Names | Apolipoprotein CIII, apolipoprotein, apolipoproteins |
| Source | Human Plasma |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; |
| Recombinant | No |
| Format | Liquid |
| Storage | -70°C; Frozen in 10 mM NH4HCO3 , pH 7.4 |
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Provided below are standard protocols that you may find useful for product applications.
Background
Apo CIII inhibits the activation of lipoprotein lipase by Apo CII. Reduced levels of Apo CIII result in higher fatty acid uptake from plasma triglycerides into adipose tissue. Thus, Apo CIII is a potential target for treatment of obesity and insulin resistance. The normal plasma concentration of Apo CIII is 8-15 mg per 100 ml.
References
Protter A.A.,et al.DNA 3:449-456(1984).
Levy-Wilson B.,et al.DNA 3:359-364(1984).
Karathanasis S.K.,et al.J. Lipid Res. 26:451-456(1985).
Sharpe C.R.,et al.Nucleic Acids Res. 12:3917-3932(1984).
Fullerton S.M.,et al.Hum. Genet. 115:36-56(2004).
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