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Cathepsin G, Human Neutrophil recombinant protein
Cathepsin G
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P08311 |
|---|---|
| Calculated MW | 23.5 kDa |
| Gene ID | 1511 |
|---|---|
| Gene Symbol | CTSG |
| Other Names | Cathepsin G, CTSG |
| Source | Human Neutrophil |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; |
| Recombinant | No |
| Application Notes | Deionized H₂O |
| Format | Lyophilized protein |
| Storage | -20°C; Salt- free lyophilized solid |
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Provided below are standard protocols that you may find useful for product applications.
Background
Cathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis.
References
Salvesen G.,et al.Biochemistry 26:2289-2293(1987).
Hohn P.A.,et al.J. Biol. Chem. 264:13412-13419(1989).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Avril L.E.,et al.FEBS Lett. 345:81-86(1994).
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