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ACAT-2, human recombinant protein
Acetyl-CoA acetyltransferase cytosolic, Cytosolic acetoacetyl-CoA thiolase, ACAT2, Acetyl CoA transf
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BWD1 |
|---|---|
| Calculated MW | 41.3 kDa |
| Gene ID | 39 |
|---|---|
| Gene Symbol | THIC |
| Other Names | Acetyl-CoA acetyltransferase cytosolic, Cytosolic acetoacetyl-CoA thiolase, ACAT2, Acetyl CoA transferase-like protein, ACAT-2, Sterol O-acyltransferase 2, Acyl-coenzyme A:cholesterol acyltransferase 2, Cholesterol acyltransferase 2 |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; ≥95% |
| Recombinant | Yes |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered solution (1 mg/ml) in 10 mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Acetyl-Coenzyme A acetyltransferase 2 (ACAT2) is an enzyme involved in lipid metabolism. Patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3 prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.
References
Song X.-Q.,et al.Biochem. Biophys. Res. Commun. 201:478-485(1994).
Chen H.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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