|Calculated MW||30.0 kDa|
|Other Names||Angiostatin K1-4, Angiostatin Kringles 1-4, plasminogen|
|Application Notes||Reconstitute in sterile distilled H₂O or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.|
|Storage||-20°C; From 20 mM Sodium Acetate, pH 5.5, 4% mannitol|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. Displays increased inhibitory activity (ED₅₀ =70 nM) relative to kringles 1-4 (ED₅₀ = 135 nM). Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth.
Petersen T.E.,et al.J. Biol. Chem. 265:6104-6111(1990).
Forsgren M.,et al.FEBS Lett. 213:254-260(1987).
Browne M.J.,et al.Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Sottrup-Jensen L.,et al.Submitted (JUL-1977) to the PIR data bank.
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