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Lipocalin-2, human recombinant protein
Neutrophil gelatinase-associated lipocalin, NGAL, p25, 25 kDa alpha-2-microglobulin-related subunit
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P80188 |
|---|---|
| Calculated MW | 20 kDa |
| Gene ID | 3934 |
|---|---|
| Gene Symbol | LCN2 |
| Other Names | Neutrophil gelatinase-associated lipocalin, NGAL, p25, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3, LCN2. |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; ≥95% |
| Recombinant | Yes |
| Application Notes | Reconstitute in H₂O to a concentration 0.1-1 mg/ml. The solution can then be further diluted to other aqueous solutions. |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and lyophilized with no additives |
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Provided below are standard protocols that you may find useful for product applications.
Background
Lipocalin-2 (LCN-2), a secreted glycoprotein, is an adipokine that potentially connects obesity and its related adipose inflammation. Lipocalin-2 has also been implicated in a variety of processes including cell differentiation, tumorigenesis, and apoptosis. The recombinant human Lipocalin-2 consisting of 178 amino acids (a.a. 21-198, Accession# NP_00555) was expressed from E. coli and purified using proprietary technology.
References
Bundgaard J.R.,et al.Biochem. Biophys. Res. Commun. 202:1468-1475(1994).
Cowland J.B.,et al.Genomics 45:17-23(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
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