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IL-31, mouse recombinant protein
Interleukin 31, IL31, IL-29
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6EAL8 |
|---|---|
| Calculated MW | 15.7 kDa |
| Gene ID | 76399 |
|---|---|
| Gene Symbol | IL31 |
| Other Names | Interleukin 31, IL31 |
| Gene Source | Mouse |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥97% |
| Assay2&Purity2 | HPLC; NA |
| Recombinant | Yes |
| Sequence | MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C |
| Application Notes | Reconstitute in sterile H₂O at a concentration of 0.1mg/ml. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. Reconstituted IL-31 should be stored in working aliquots at -20°C. |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered white powder lyophilized from a solution containing 10 mM sodium phosphate buffer pH 7.5. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Interleukin-31 (IL-31) is an immunoregulatory cytokine that is mainly expressed by activated TH2 cells. IL-31 signals through the IL-31 Receptor (IL-31RA) and the oncostain receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 has a role in inflammatory skin diseases. Recombinant mouse IL-31 is a non-glycosylated protein, containing 141 amino acids, with a mass of 15.7 kDa.
References
Dillon S.R.,et al.Nat. Immunol. 5:752-760(2004).
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