Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
Human recombinant protein PRDX 5
Human Recombinant PRDX 5
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P30044 |
|---|---|
| Concentration | 1 |
| Calculated MW | 17 kDa |
| Gene ID | 25824 |
|---|---|
| Gene Symbol | PRDX5 |
| Other Names | Peroxiredoxin 5, ACR1, AOEB116, B116, PLP, PMP20, PRDX6, PRXV, SBBI10. |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Sequence | MAPIKVGDAI PAVEVFEGEP GNKVNLAELF KGKKGVLFGV PGAFTPGCSK THLPGFVEQA EALKAKGVQV VACLSVNDAF VTGEWGRAHK AEGKVRLLAD PTGAFGKETD LLLDDSLVSI FGNRRLKRFS MVVQDGIVKA LNVEPDGTGL TCSLAPNIIS QL. |
| Format | Liquid |
| Storage | -80°C; 1 mg/ml solution in 20 mM HEPES buffer (pH 7.4). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Peroxiredoxin-5, mitochondrial in humans is encoded by the PRDX5 gene. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. It interacts with peroxisome receptor 1. In human cells, it has been shown that PRDX5 can be addressed to mitochondria, peroxisomes, the cytosol, and the nucleus.
References
Kropotov A.,et al.Eur. J. Biochem. 260:336-346(1999).
Yamashita H.,et al.J. Biol. Chem. 274:29897-29904(1999).
Knoops B.,et al.J. Biol. Chem. 274:30451-30458(1999).
Zhou Y.,et al.Biochem. Biophys. Res. Commun. 268:921-927(2000).
Seo M.S.,et al.J. Biol. Chem. 275:20346-20354(2000).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
