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Human recombinant protein PRDX 6
Human Recombinant PRDX 6
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P30041 |
|---|---|
| Concentration | 1 |
| Calculated MW | 27.1 kDa |
| Gene ID | 9588 |
|---|---|
| Gene Symbol | PRDX6 |
| Other Names | Peroxiredoxin 6, 1-Cys, aiPLA2, AOP2, NSGPx, p29, PRX. |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Sequence | MGSSHHHHHH SSGLVPRGSH MPGGLLLGDV APNFEANTTV GRIRFHDFLG DSWGILFSHP RDFTPVCTTE LGRAAKLAPE FAKRNVKLIA LSIDSVEDHL AWSKDINAYN CEEPTEKLPF PIIDDRNREL AILLGMLDPA EKDEKGMPVT ARVVFVFGPD KKLKLSILYP ATTGRNFDEI LRVVISLQLT AEKRVATPVD WKDGDSVMVL PTIPEEEAKK LFPKGVFTKE LPSGKKYLRY TPQP |
| Format | Liquid |
| Storage | -80°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Peroxiredoxin 6, also known as PRDX 6, is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell and can reduce H2O2 and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
References
Kim T.-S.,et al.J. Biol. Chem. 272:2542-2550(1997).
Kim T.-S.,et al.J. Biol. Chem. 272:10981-10981(1997).
Frank S.,et al.Oncogene 14:915-921(1997).
Nagase T.,et al.DNA Res. 2:37-43(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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