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E. Coli recombinant protein TRXB
E. Coli Recombinant TRXB
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P0A9P4 |
|---|---|
| Concentration | 1 |
| Calculated MW | 34.6 kDa |
| Gene ID | 949054 |
|---|---|
| Gene Symbol | TRXB |
| Other Names | Thioredoxin reductase |
| Gene Source | E. Coli |
| Source | E. Coli |
| Assay&Purity | SDS-PAGE; ≥90% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Sequence | MGTTKHSKLL ILGSGPAGYT AAVYAARANL QPVLITGMEK GGQLTTTTEV ENWPGDPNDL TGPLLMERMH EHATKFETEI IFDHINKVDL QNRPFRLNGD NGEYTCDALI IATGASARYL GLPSEEAFKG RGVSACATCD GFFYRNQKVA VIGGGNTAVE EALYLSNIAS EVHLIHRRDG FRAEKILIKR LMDKVENGNI ILHTNRTLEE VTGDQMGVTG VRLRDTQNSD NIESLDVAGL FVAIGHSPNT AIFEGQLELE NGYIKVQSGI HGNATQTSIP GVFAAGDVMD HIYRQAITSA GTGCMAALDA ERYLDGLADA K. |
| Format | Liquid |
| Storage | -80°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol and 1mM DTT. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Thioredoxin reductases are the only known enzymes to reduce thioredoxin. Two classes of thioredoxin reductase have been identified: one class in bacteria and some eukaryotes and one in animals. Both classes are flavoproteins which function as homodimers. TRXB (Thioredoxin reductase) is a ubiquitous enzyme which is involved in many cellular processes such as cell growth, p53 activity, and protection against oxidation stress
References
Russel M.,et al.J. Biol. Chem. 263:9015-9019(1988).
Oshima T.,et al.DNA Res. 3:137-155(1996).
Blattner F.R.,et al.Science 277:1453-1462(1997).
Hayashi K.,et al.Mol. Syst. Biol. 2:E1-E5(2006).
Delaney J.M.,et al.J. Bacteriol. 175:166-175(1993).
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