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Mouse recombinant protein GSTMu 1
Mouse Recombinant GSTMu 1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P10649 |
|---|---|
| Concentration | 1 |
| Calculated MW | 28.1 kDa |
| Gene ID | 14862 |
|---|---|
| Gene Symbol | GSTMu1 |
| Other Names | GSTM1, GST class-mu1, GST 1-1, pmGT10 |
| Gene Source | Mouse |
| Source | E. Coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Sequence | MGSSHHHHHH SSGLVPRGSH MPMILGYWNV RGLTHPIRML LEYTDSSYDE KRYTMGDAPD FDRSQWLNEK FKLGLDFPNL PYLIDGSHKI TQSNAILRYL ARKHHLDGET EEERIRADIV ENQVMDTRMQ LIMLCYNPDF EKQKPEFLKT IPEKMKLYSE FLGKRPWFAG DKVTYVDFLA YDILDQYRMF EPKCLDAFPN LRDFLARFEG LKKISAYMKS SRYIATPIFS KMAHWSNK |
| Format | Liquid |
| Storage | -80°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, and 10% glycerol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
GSTM1 is a glutathione S-transferase that belongs to the mu class. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur). The reactions utilizing glutathione contribute the transformation of a wide variety of electrophiles, including reactive products of lipid, protein, carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress.
References
Pearson W.R.,et al.J. Biol. Chem. 263:13324-13332(1988).
Townsend A.J.,et al.J. Biol. Chem. 264:21582-21590(1989).
Reinhart J.,et al.Arch. Biochem. Biophys. 303:383-393(1993).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Pearson W.R.,et al.J. Biol. Chem. 258:2052-2062(1983).
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