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Betacellulin, Murine recombinant protein

BTC

     
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Product info
Primary Accession Q05928
Calculated MW 9 kDa
Additional Info
Gene ID 12223
Gene Symbol BTC
Other Names BTC
Gene Source Mouse
Source E.coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC;
Recombinant Yes
Sequence DGNTTRTPET NGSLCGAPGE NCTGTTPRQK VKTHFSRCPK QYKHYCIHGR CRFVVDEQTP SCICEKGYFG ARCERVDLFY
Target/Specificity Betacellulin
Application Notes Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Format Lyophilized powder
Storage -20°C; Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
Citations (0)
citation

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Background

Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant murine Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein precursor.

References

Shing Y.,et al.Science 259:1604-1607(1993).
Carninci P.,et al.Science 309:1559-1563(2005).
Oh Y.S.,et al.PLoS ONE 6:E23894-E23894(2011).

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Discontinued
Cat# PBV10754r-10
Size:

Ordering Information

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