Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
RBP4, rat recombinant protein
Retinol Binding Protein 4, Plasma retinol-binding protein, PRBP, RBP
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P04916 |
|---|---|
| Calculated MW | ~23.0 kDa (monomer). Rat RBP4 (aa 19-201) is fused at the C-terminus to a His-Tag |
| Gene ID | 25703 |
|---|---|
| Gene Symbol | RBP4 |
| Other Names | Retinol Binding Protein 4, Plasma retinol-binding protein, PRBP, RBP |
| Gene Source | Rat |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥90% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Target/Specificity | RBP4 |
| Format | Liquid |
| Storage | -20°C; 0.2 µm-filtered solution in 55 mM TRIS-Cl, pH 8.2 containing 150 mM NaCl. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Retinol binding protein 4 (RBP4; RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
References
Laurent B.C.,et al.J. Biol. Chem. 260:11476-11480(1985).
Sundelin J.,et al.J. Biol. Chem. 260:6472-6480(1985).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Shipping Information
