TGF-β1, human recombinant protein (E. Coli)
Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB, TGF-b 1, LAP, TGFB1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P01137 |
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Calculated MW | 15.09 kDa (279 to 390 aa + NT-His Tag). |
Gene ID | 7040 |
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Gene Symbol | TGFB1 |
Other Names | Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB, TGF-b 1, LAP, TGFB1. |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥95% |
Assay2&Purity2 | N/A; |
Recombinant | Yes |
Target/Specificity | TGF-β1 |
Application Notes | Centrifuge the vial prior to opening. Reconstitute in water to a stock concentration of 1 mg/ml and further dilute in buffer of choice. |
Format | Lyophilized |
Storage | -20°C; Lyophilized without any additives. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transforming growth factor-betas (TGF-βs) mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGF-Beta 1, TGF-Beta 2 and TGF-Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-beta 1 is involved in hematopoiesis and endothelial differentiation.
References
Derynck R.,et al.Nucleic Acids Res. 15:3188-3189(1987).
Derynck R.,et al.Nature 316:701-705(1985).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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