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Human CellExp™ TIM3/HAVR2 Protein, Human Recombinant
Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing pr
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8TDQ0 |
|---|---|
| Calculated MW | This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 20.7 kDa. The predicted N-terminus is Ser 22. DTT-reduced Protein migrates as 28-48 kDa due to glycosylation. |
| Gene ID | 84868 |
|---|---|
| Other Names | Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3 |
| Gene Source | Human |
| Source | HEK 293 cells |
| Assay&Purity | SDS-PAGE;≥95% |
| Recombinant | Yes |
| Sequence | Ser 22 - Arg 220 |
| Target/Specificity | TIM3/HAVR2 |
| Application Notes | Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH7.4) to a stock solution of 400 µg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage. |
| Format | Dry powder |
| Storage | 4°C in lyophilized state;Lyophilized powder |
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.
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