Thymosin alpha 1
Prothymosin alpha, PTMA, TMSA
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P06454 |
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Calculated MW | 3.1 kDa |
Gene ID | 5757 |
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Other Names | Prothymosin alpha, PTMA, TMSA |
Gene Source | Human |
Source | N/A |
Assay&Purity | HPLC;> 99% |
Recombinant | No |
Target/Specificity | PTMA |
Application Notes | Reconstitute in Trifluoro acetic acid |
Format | Lyophilized |
Storage | -20°C;N/A |
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Provided below are standard protocols that you may find useful for product applications.
Background
Thymosin α1 is a peptide fragment derived from prothymosin alpha, a protein that in humans is encoded by the PTMA gene. Thymosin α1 is believed to be a major component of Thymosin Fraction 5 responsible for the activity of that preparation in restoring immune function in animals lacking thymus glands. It was the first of the peptides from Thymosin Fraction 5 to be completely sequenced and synthesized. Unlike β thymosins, to which it is genetically and chemically unrelated, thymosin α1 is produced as a 28-amino acid fragment, from a longer, 113-amino acid precursor, prothymosin α. It has been found to enhance cell-mediated immunity in humans as well as experimental animals.
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