Nucleocapsid S-RBD Fusion
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P0DTC2 & P0DTC9 |
|---|---|
| Species | SARS-CoV-2 |
| Sequence | Full length of nucleocapsid protein and spike protein RBD region |
| Purity | > 75% as analyzed by SDS-PAGE |
| Endotoxin Level | < 0.2 EU/ µg of protein by gel clotting method |
| Biological Activity | SARS-CoV-2 Nucleocapsid S-RBD Fusion (His tag) can bind to both human ACE2 (Cat. No.: Z03484) and nucleocapsid antibody (Cat. No.: A02039) in functional ELISA assay. |
| Expression System | 293 Cells |
| Theoretical Molecular Weight | 74.9 kDa |
| Formulation | Supplied as a solution in PBS pH 7.4 containing 10% glycerol. |
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -20°C or below. Avoid repeated freeze-thaw cycles. |
| Target Background | SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid. It is the most abundant protein for coronavirus. Because of the strong immunogenicity of coronavirus Nucleocapsid, it is believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. SARS-CoV-2 Spike Protein (RBD) also has the potential value for the diagnosis of the virus. |
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