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GRIN3B Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | O60391 |
| Other Accession | NP_619635.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 112992 Da |
| Antigen Region | 904-933 aa |
| Gene ID | 116444 |
|---|---|
| Other Names | Glutamate receptor ionotropic, NMDA 3B, GluN3B, N-methyl-D-aspartate receptor subtype 3B, NMDAR3B, NR3B, GRIN3B |
| Target/Specificity | This GRIN3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 904-933 amino acids from the C-terminal region of human GRIN3B. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GRIN3B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GRIN3B |
|---|---|
| Function | NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane Note=Requires the presence of GRIN1 to be targeted at the plasma membrane. |
Provided below are standard protocols that you may find useful for product applications.
Background
GRIN3B is a NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. It is mediated by glycine.
References
Sedaghati, M., et al. Eur. J. Pharmacol. 633 (1-3), 50-54 (2010) :
Saus, E., et al. J Psychiatr Res (2010) In press :
Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
Liu, H.P., et al. Dement Geriatr Cogn Disord 28(6):521-527(2009)
Niemann, S., et al. Neurology 70(9):666-676(2008)
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