GRIN3B Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | O60391 |
Other Accession | NP_619635.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 112992 Da |
Antigen Region | 904-933 aa |
Gene ID | 116444 |
---|---|
Other Names | Glutamate receptor ionotropic, NMDA 3B, GluN3B, N-methyl-D-aspartate receptor subtype 3B, NMDAR3B, NR3B, GRIN3B |
Target/Specificity | This GRIN3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 904-933 amino acids from the C-terminal region of human GRIN3B. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GRIN3B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GRIN3B |
---|---|
Function | NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. |
Cellular Location | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane Note=Requires the presence of GRIN1 to be targeted at the plasma membrane. |
Provided below are standard protocols that you may find useful for product applications.
Background
GRIN3B is a NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. It is mediated by glycine.
References
Sedaghati, M., et al. Eur. J. Pharmacol. 633 (1-3), 50-54 (2010) :
Saus, E., et al. J Psychiatr Res (2010) In press :
Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
Liu, H.P., et al. Dement Geriatr Cogn Disord 28(6):521-527(2009)
Niemann, S., et al. Neurology 70(9):666-676(2008)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.