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ADRM1 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a full-length recombinant ADRM1.

     
  • WB - ADRM1 Antibody (monoclonal) (M02) AT1061a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (68.64 KDa) .
    detail
  • WB - ADRM1 Antibody (monoclonal) (M02) AT1061a
    ADRM1 monoclonal antibody (M02), clone 3D11. Western Blot analysis of ADRM1 expression in HeLa ( (Cat # AT1061a )
    detail
  • WB - ADRM1 Antibody (monoclonal) (M02) AT1061a
    Western Blot analysis of ADRM1 expression in transfected 293T cell line by ADRM1 monoclonal antibody (M02), clone 3D11.

    Lane 1: ADRM1 transfected lysate(42.2 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • E - ADRM1 Antibody (monoclonal) (M02) AT1061a
    Detection limit for recombinant GST tagged ADRM1 is 0.03 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q16186
Other Accession BC017245
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 3D11
Calculated MW 42153 Da
Additional Information
Gene ID 11047
Other Names Proteasomal ubiquitin receptor ADRM1, 110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Proteasome regulatory particle non-ATPase 13, hRpn13, Rpn13 homolog, ADRM1, GP110
Target/Specificity ADRM1 (AAH17245.1, 18 a.a. ~ 407 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsADRM1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Two transcript variants encoding the same protein have been found for this gene.

References

Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13). Mazumdar T, et al. Proc Natl Acad Sci U S A, 2010 Aug 3. PMID 20634424.Structure of proteasome ubiquitin receptor hRpn13 and its activation by the scaffolding protein hRpn2. Chen X, et al. Mol Cell, 2010 May 14. PMID 20471946.Functional differences between two major ubiquitin receptors in the proteasome; S5a and hRpn13. Elangovan M, et al. Biochem Biophys Res Commun, 2010 May 28. PMID 20417181.Adrm1 interacts with Atp6v0d2 and regulates osteoclast differentiation. Kim T, et al. Biochem Biophys Res Commun, 2009 Dec 18. PMID 19818731.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.

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$ 350.00
Cat# AT1061a
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