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ADRM1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a full-length recombinant ADRM1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q16186 |
| Other Accession | BC017245 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 3D11 |
| Calculated MW | 42153 Da |
| Gene ID | 11047 |
|---|---|
| Other Names | Proteasomal ubiquitin receptor ADRM1, 110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Proteasome regulatory particle non-ATPase 13, hRpn13, Rpn13 homolog, ADRM1, GP110 |
| Target/Specificity | ADRM1 (AAH17245.1, 18 a.a. ~ 407 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ADRM1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Two transcript variants encoding the same protein have been found for this gene.
References
Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13). Mazumdar T, et al. Proc Natl Acad Sci U S A, 2010 Aug 3. PMID 20634424.Structure of proteasome ubiquitin receptor hRpn13 and its activation by the scaffolding protein hRpn2. Chen X, et al. Mol Cell, 2010 May 14. PMID 20471946.Functional differences between two major ubiquitin receptors in the proteasome; S5a and hRpn13. Elangovan M, et al. Biochem Biophys Res Commun, 2010 May 28. PMID 20417181.Adrm1 interacts with Atp6v0d2 and regulates osteoclast differentiation. Kim T, et al. Biochem Biophys Res Commun, 2009 Dec 18. PMID 19818731.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.
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