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ENTH Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant ENTH.

     
  • IF - ENTH Antibody (monoclonal) (M03) AT1915a
    Immunofluorescence of monoclonal antibody to CLINT1 on HeLa cell . [antibody concentration 10 ug/ml]
    detail
  • WB - ENTH Antibody (monoclonal) (M03) AT1915a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.85 KDa) .
    detail
  • WB - ENTH Antibody (monoclonal) (M03) AT1915a
    ENTH monoclonal antibody (M03), clone 1E6. Western Blot analysis of ENTH expression in PC-12((Cat # AT1915a )
    detail
  • WB - ENTH Antibody (monoclonal) (M03) AT1915a
    ENTH monoclonal antibody (M03), clone 1E6. Western Blot analysis of ENTH expression in Raw 264.7((Cat # AT1915a )
    detail
  • WB - ENTH Antibody (monoclonal) (M03) AT1915a
    ENTH monoclonal antibody (M03), clone 1E6. Western Blot analysis of ENTH expression in Jurkat ( (Cat # AT1915a )
    detail
  • WB - ENTH Antibody (monoclonal) (M03) AT1915a
    ENTH monoclonal antibody (M03), clone 1E6. Western Blot analysis of ENTH expression in NIH/3T3((Cat # AT1915a )
    detail
  • IHC - ENTH Antibody (monoclonal) (M03) AT1915a
    Immunoperoxidase of monoclonal antibody to CLINT1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
    detail
  • E - ENTH Antibody (monoclonal) (M03) AT1915a
    Detection limit for recombinant GST tagged CLINT1 is 0.3 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, E
Primary Accession Q14677
Other Accession NM_014666
Reactivity Human, Mouse, Rat
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1E7
Calculated MW 68259 Da
Additional Information
Gene ID 9685
Other Names Clathrin interactor 1, Clathrin-interacting protein localized in the trans-Golgi region, Clint, Enthoprotin, Epsin-4, Epsin-related protein, EpsinR, CLINT1, ENTH, EPN4, EPNR, KIAA0171
Target/Specificity ENTH (NP_055481.1, 161 a.a. ~ 261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsENTH Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants.

References

Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. Saus E, et al. J Psychiatr Res, 2010 Apr 14. PMID 20398908.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.The epsin 4 gene is associated with psychotic disorders in families of Latin American origin. Escamilla M, et al. Schizophr Res, 2008 Dec. PMID 18929466.Failure to confirm an association between Epsin 4 and schizophrenia in a Japanese population. Richards M, et al. J Neural Transm, 2008 Sep. PMID 18696005.

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$ 350.00
Cat# AT1915a
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Availability: 7-10 days
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