|Other Names||7SK snRNA methylphosphate capping enzyme, MePCE, 211-, Bicoid-interacting protein 3 homolog, Bin3 homolog, MEPCE, BCDIN3|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13105c was selected from the Center region of MEPCE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.|
|Tissue Location||Expressed in chronic myeloid leukemia cells, adrenal gland, brain, cerebellum, kidney, lung, mammary gland and testis. Weakly or not expressed in other tissues|
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Provided below are standard protocols that you may find useful for product applications.
S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.
Xue, Y., et al. Nucleic Acids Res. 38(2):360-369(2010)Krueger, B.J., et al. Nucleic Acids Res. 36(7):2219-2229(2008)Kaneko, S., et al. Proc. Natl. Acad. Sci. U.S.A. 104(45):17620-17625(2007)Jeronimo, C., et al. Mol. Cell 27(2):262-274(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)
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