|Other Names||Rho GTPase-activating protein 5, Rho-type GTPase-activating protein 5, p190-B, ARHGAP5, RHOGAP5|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8753c was selected from the Center region of human ARHGAP5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||GTPase-activating protein for Rho family members (PubMed:8537347).|
|Cellular Location||Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also membrane-associated in a fibrillar pattern that colocalizes with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin.|
|Tissue Location||Detected in skin fibroblasts (at protein level) (PubMed:8537347).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
ARHGAP5 is a GTPase-activating protein for Rho family members. It may play a role in the reduction of the p21rasGTPase-activating potential of p120GAP.
Foster,R., et.al., Mol. Cell. Biol. 14 (11), 7173-7181 (1994)
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