ARHGAP5 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q13017 |
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Clone Names | 90819151 |
Gene ID | 394 |
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Other Names | Rho GTPase-activating protein 5, Rho-type GTPase-activating protein 5, p190-B, ARHGAP5, RHOGAP5 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8753c was selected from the Center region of human ARHGAP5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ARHGAP5 |
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Synonyms | RHOGAP5 |
Function | GTPase-activating protein for Rho family members (PubMed:8537347). |
Cellular Location | Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also membrane-associated in a fibrillar pattern that colocalizes with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin. |
Tissue Location | Detected in skin fibroblasts (at protein level) (PubMed:8537347). |
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Provided below are standard protocols that you may find useful for product applications.
Background
ARHGAP5 is a GTPase-activating protein for Rho family members. It may play a role in the reduction of the p21rasGTPase-activating potential of p120GAP.
References
Foster,R., et.al., Mol. Cell. Biol. 14 (11), 7173-7181 (1994)
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