|Other Names||Psychosine receptor, G-protein coupled receptor 65, T-cell death-associated gene 8 protein, GPR65, TDAG8|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids (PubMed:11309421). Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance (PubMed:27287411). May have a role in activation-induced cell death or differentiation of T-cells (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a role in activation-induced cell death or differentiation of T-cells.
Mogi, C., et al. J. Immunol. 182(5):3243-3251(2009)Ishii, S., et al. J. Biol. Chem. 280(10):9083-9087(2005)Radu, C.G., et al. Proc. Natl. Acad. Sci. U.S.A. 102(5):1632-1637(2005)
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