|Dilution||IHC-P (10 µg/ml)|
|Other Names||Psychosine receptor, G-protein coupled receptor 65, T-cell death-associated gene 8 protein, GPR65, TDAG8|
|Target/Specificity||Human GPR65. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except VCL (50%), CPS1 (39%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||GPR65 / TDAG8 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids (PubMed:11309421). Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance (PubMed:27287411). May have a role in activation-induced cell death or differentiation of T-cells (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a role in activation- induced cell death or differentiation of T-cells.
Kyaw H.,et al.DNA Cell Biol. 17:493-500(1998).
Heilig R.,et al.Nature 421:601-607(2003).
Im D.-S.,et al.J. Cell Biol. 153:429-434(2001).
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