|Other Accession||NM_003608, NP_003599|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Dog|
|Alias Symbol||TDAG8, hTDAG8|
|Other Names||Psychosine receptor, G-protein coupled receptor 65, T-cell death-associated gene 8 protein, GPR65, TDAG8|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-GPR65 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||GPR65 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids (PubMed:11309421). Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance (PubMed:27287411). May have a role in activation-induced cell death or differentiation of T-cells (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
Kyaw H.,et al.DNA Cell Biol. 17:493-500(1998).
Heilig R.,et al.Nature 421:601-607(2003).
Im D.-S.,et al.J. Cell Biol. 153:429-434(2001).
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