Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.Target of the Week - GSK3 Antibodies
Mar 02, 2015
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Dear Cancer Researcher, Glycogen synthase kinase 3 (GSK3) regulates glycogen synthesis in response to insulin. It is a ubiquitously expressed serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK3 is a critical downstream element of the PI3K/Akt cell survival pathway whose activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK3 alpha and Ser9 of GSK3 alpha. GSK3 is a component of Wnt signaling and has been shown to regulate cyclin D1 proteolysis and subcellular localization. To find the right antibody for your research, please visit Abgent GSK Antibodies. |
 Monoclonal Antibody to GSK3Cat# AO1342a |
 Rabbit Monoclonal GSK3 alphaAntibody Cat# AJ1334a |
 Rabbit Polyclonal GSK3 alpha Antibody Phosphospecific (Ser9)Cat# AP50219 |
 Polyclonal GSK3 alpha Antibody Phosphospecific (Ser21)Cat# AP50457 |
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