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Anti-SFTPA1 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8IWL2 |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Clonality | Polyclonal |
| Format | Liquid |
| Description | Rabbit IgG polyclonal antibody for Pulmonary surfactant-associated protein A1(SFTPA1) detection. Tested with WB in Human;Rat. |
| Gene ID | 653509 |
|---|---|
| Other Names | Pulmonary surfactant-associated protein A1, PSP-A, PSPA, SP-A, SP-A1, 35 kDa pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-4, SFTPA1, COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B |
| Calculated MW | 26242 MW KDa |
| Application Details | Western blot, 0.1-0.5 µg/ml, Human, Rat |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film. |
| Protein Name | Pulmonary surfactant-associated protein A1(PSP-A/PSPA/SP-A/SP-A1) |
| Contents | Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify Carrier Free" or "No BSA" in your order note. " |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human SFTPA1(221-236aa KEQCVEMYTDGQWNDR), different from the rat sequence by two amino acids. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year, at 4˚C for one month. Avoid repeated freezing and thawing. |
| Sequence Similarities | Belongs to the SFTPA family. |
| Name | SFTPA1 |
|---|---|
| Synonyms | COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B |
| Function | In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages (By similarity). |
| Cellular Location | Secreted. Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Surfactant protein A is an innate immune system collectin. The gene encoding SP-A map to mouse chromosome 14.1. Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.
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