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Anti-Rab3C Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q96E17 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Ras-related protein Rab-3C(RAB3C) detection. Tested with WB in Human;Mouse;Rat. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 115827 |
|---|---|
| Other Names | Ras-related protein Rab-3C, RAB3C |
| Calculated MW | 25952 MW KDa |
| Application Details | Western blot, 0.1-0.5 µg/ml, Human, Rat, Mouse |
| Subcellular Localization | Cell membrane ; Lipid-anchor ; Cytoplasmic side . |
| Tissue Specificity | Expressed in brain, placenta and lung. . |
| Protein Name | Ras-related protein Rab-3C |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Rab3C(204-217aa AITAAKQNTRLKET), different from the related mouse and rat sequences by one amino acid. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Name | RAB3C (HGNC:30269) |
|---|---|
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side |
| Tissue Location | Expressed in brain, placenta and lung. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Ras-related protein Rab-3C is a protein that in humans is encoded by the RAB3C gene. It is mapped to 5q11.2. RAB3C is found in brain, adrenal gland and pituitary. This gene is one of the small GTPases implicated in the regulation of vesicular trafficking between membrane compartments. RAB3C gene contains 6 exons and spans more than 310 kb. The function of this gene is transporting protein, and probably involved in vesicular traffic. RAB3C can interact with RIMS2, RPH3A and RPH3AL.
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