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Anti-MEK5 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, ICC |
|---|---|
| Primary Accession | Q13163 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-MEK5 Rabbit Monoclonal Antibody . Tested in WB, ICC/IF applications. This antibody reacts with Human. |
| Gene ID | 5607 |
|---|---|
| Other Names | Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, 2.7.12.2, MAPK/ERK kinase 5, MEK 5, MAP2K5, MEK5, MKK5, PRKMK5 |
| Calculated MW | 50112 MW KDa |
| Application Details | WB 1:1000-1:2000 ICC/IF 1:50-1:200 |
| Tissue Specificity | Expressed in many adult tissues. Abundant in heart and skeletal muscle. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: HCE-13 |
| Immunogen | A synthesized peptide derived from human MEK5 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | MAP2K5 |
|---|---|
| Synonyms | MEK5, MKK5, PRKMK5 |
| Function | Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. As part of the MAPK/ERK signaling pathway, acts as a negative regulator of apoptosis in cardiomyocytes via promotion of STUB1/CHIP-mediated ubiquitination and degradation of ICER-type isoforms of CREM (By similarity). |
| Tissue Location | Expressed in many adult tissues. Abundant in heart and skeletal muscle |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13465
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