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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-AGTR2/Angiotensin Ii Type 2 Receptor Rabbit Monoclonal Antibody
Anti-AGTR2/Angiotensin Ii Type 2 Receptor Rabbit Monoclonal Antibody
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Application 
| WB, IP |
|---|---|
| Primary Accession | P50052 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-AGTR2/Angiotensin Ii Type 2 Receptor Rabbit Monoclonal Antibody . Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 186 |
|---|---|
| Other Names | Type-2 angiotensin II receptor, Angiotensin II type-2 receptor, AT2 receptor, AGTR2 {ECO:0000303|PubMed:7790004, ECO:0000312|HGNC:HGNC:338} |
| Calculated MW | 41184 MW KDa |
| Application Details | WB 1:1000-1:2000 IP 1:50 |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine.. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: FIO-1 |
| Immunogen | A synthesized peptide derived from human AGTR2 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | AGTR2 {ECO:0000303|PubMed:7790004, ECO:0000312|HGNC:HGNC:338} |
|---|---|
| Function | Receptor for angiotensin II, a vasoconstricting peptide (PubMed:28379944, PubMed:29967536, PubMed:31899086, PubMed:8185599). Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways (PubMed:28379944). Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation (PubMed:15123706). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P35374}; Multi-pass membrane protein |
| Tissue Location | In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13673
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