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> home > Products > Primary Antibodies > Signal Transduction > Anti-Hsp105 Rabbit Monoclonal Antibody
Anti-Hsp105 Rabbit Monoclonal Antibody
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Application 
| WB, IHC, IF, ICC, IP |
|---|---|
| Primary Accession | Q92598 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Hsp105 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 10808 |
|---|---|
| Other Names | Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein, Heat shock protein family H member 1, HSPH1, HSP105, HSP110, KIAA0201 |
| Calculated MW | 96865 MW KDa |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:50 |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: IOG-8 |
| Immunogen | A synthesized peptide derived from human Hsp105 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | HSPH1 |
|---|---|
| Synonyms | HSP105, HSP110, KIAA0201 |
| Function | Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release (PubMed:24318877). Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13856
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