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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-Rhodopsin Rabbit Monoclonal Antibody
Anti-Rhodopsin Rabbit Monoclonal Antibody
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Application 
| WB, IHC |
|---|---|
| Primary Accession | P08100 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Rhodopsin Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human, Rat. |
| Gene ID | 6010 |
|---|---|
| Other Names | Rhodopsin, Opsin-2, RHO, OPN2 |
| Calculated MW | 38893 MW KDa |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 |
| Subcellular Localization | Membrane ; Multi-pass membrane protein. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia. |
| Tissue Specificity | Rod shaped photoreceptor cells which mediates vision in dim light. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AADI-18 |
| Immunogen | A synthesized peptide derived from human Rhodopsin |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | RHO |
|---|---|
| Synonyms | OPN2 |
| Function | Photoreceptor required for image-forming vision at low light intensity (PubMed:7846071, PubMed:8107847). Required for photoreceptor cell viability after birth (PubMed:12566452, PubMed:2215617). Light- induced isomerization of the chromophore 11-cis-retinal to all-trans- retinal triggers a conformational change that activates signaling via G-proteins (PubMed:26200343, PubMed:28524165, PubMed:28753425, PubMed:8107847). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:26200343, PubMed:28524165). |
| Cellular Location | Membrane; Multi-pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia |
| Tissue Location | Rod shaped photoreceptor cells which mediate vision in dim light |
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO14005
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