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Anti-PHOX2B Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF, ICC |
|---|---|
| Primary Accession | Q99453 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-PHOX2B Monoclonal Antibody . Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse. |
| Gene ID | 8929 |
|---|---|
| Other Names | Paired mesoderm homeobox protein 2B, Neuroblastoma Phox, NBPhox, PHOX2B homeodomain protein, Paired-like homeobox 2B, PHOX2B, PMX2B |
| Calculated MW | 31621 Da |
| Application Details | WB 1:500-1:2000 IHC 1:100-1:500 ICC/IF 1:50-1:200 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AEFG-16 |
| Immunogen | A synthesized peptide derived from human PHOX2B Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | PHOX2B |
|---|---|
| Synonyms | PMX2B |
| Function | Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta- hydrolase and c-fos promoters, and of several enhancers including cAMP- response element and serum-response element. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
| Tissue Location | Expressed in neuroblastoma, brain and adrenal gland |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO14654
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