Anti-ACVR2A Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | P27037 |
Host | Rabbit |
Isotype | IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-ACVR2A Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 92 |
---|---|
Other Names | Activin receptor type-2A, 2.7.11.30, Activin receptor type IIA, ACTR-IIA, ACTRIIA, ACVR2A (HGNC:173), ACVR2 |
Calculated MW | 85 kDa |
Application Details | WB 1:500-1:2000 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 25A00 |
Immunogen | A synthesized peptide derived from human ACVR2A |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | ACVR2A (HGNC:173) |
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Synonyms | ACVR2 |
Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A (PubMed:17911401, PubMed:10652306). Mediates induction of adipogenesis by GDF6 (By similarity). |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P27038}; Single-pass type I membrane protein |

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