Anti-PTBP2 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | Q9UKA9 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-PTBP2 Rabbit Monoclonal Antibody . Tested in WB applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 58155 |
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Other Names | Polypyrimidine tract-binding protein 2, Neural polypyrimidine tract-binding protein, Neurally-enriched homolog of PTB, PTB-like protein, PTBP2 (HGNC:17662), NPTB, PTB, PTBLP |
Calculated MW | 57491 Da |
Application Details | WB 1:500-1:2000 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 31P38 |
Immunogen | A synthesized peptide derived from human PTBP2 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | PTBP2 (HGNC:17662) |
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Synonyms | NPTB, PTB, PTBLP |
Function | RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q91Z31}. |
Tissue Location | Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non-neuronal tissues |

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