Anti-Desmocollin 1 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | Q08554 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-Desmocollin 1 Rabbit Monoclonal Antibody . Tested in WB applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 1823 |
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Other Names | Desmocollin-1, Cadherin family member 1, Desmosomal glycoprotein 2/3, DG2/DG3, DSC1, CDHF1 |
Calculated MW | 99987 Da |
Application Details | WB 1:500-1:2000 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 31D56 |
Immunogen | A synthesized peptide derived from human Desmocollin 1 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | DSC1 |
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Synonyms | CDHF1 |
Function | A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion (By similarity). Required for desmosome adhesion strength between the granular layers of the epidermis, as a result moderates epidermal proliferation and differentiation (By similarity). Is therefore required to maintain postnatal epidermal barrier function and normal hair follicle morphology into adulthood (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome {ECO:0000250|UniProtKB:P55849} |
Tissue Location | Strongly expressed in epidermis, less in lymph node and tongue. |

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