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> home > Products > Primary Antibodies > Signal Transduction > Anti-Phospho-BCAR1 (Y410) Rabbit Monoclonal Antibody
Anti-Phospho-BCAR1 (Y410) Rabbit Monoclonal Antibody
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P56945 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Phospho-BCAR1 (Y410) Rabbit Monoclonal Antibody . Tested in WB applications. This antibody reacts with Human. |
| Gene ID | 9564 |
|---|---|
| Other Names | Breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, Cas scaffolding protein family member 1, p130cas, BCAR1, CAS, CASS1, CRKAS |
| Calculated MW | 93372 Da |
| Application Details | WB 1:500-1:2000 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: 32B03 |
| Immunogen | A synthesized peptide derived from human Phospho-BCAR1 (Y410) |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | BCAR1 |
|---|---|
| Synonyms | CAS, CASS1, CRKAS |
| Function | Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion (PubMed:12432078, PubMed:12832404). Implicated in induction of cell migration and cell branching (PubMed:12432078, PubMed:12832404, PubMed:17038317). Involved in the BCAR3-mediated inhibition of TGFB signaling (By similarity). |
| Cellular Location | Cell junction, focal adhesion. Cytoplasm Cell projection, axon {ECO:0000250|UniProtKB:Q61140} Note=Unphosphorylated form localizes in the cytoplasm (By similarity) Localizes to focal adhesion sites following integrin engagement (By similarity). {ECO:0000250|UniProtKB:Q61140} |
| Tissue Location | Expressed in B-cells (at protein level) (PubMed:9020138). Widely expressed with an abundant expression in the testis (PubMed:10639512). Low level of expression seen in the liver, thymus, and peripheral blood leukocytes (PubMed:10639512) |
Research Areas
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Application Protocols
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$ 370.00
Cat# ABO16732
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