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Anti-OX40L (Oxelumab), Human IgG1 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P23510 |
|---|---|
| Reactivity | Human |
| Host | Recombinant |
| Clonality | Monoclonal |
| Isotype | Human IgG1, kappa |
| Calculated MW | 21050 Da |
| Gene ID | 7292 |
|---|---|
| Alias Symbol | OX40L |
| Other Names | TNFSF4; tumor necrosis factor (TNF) superfamily member 4; OX40 ligand; OX-40L; TAX transcriptionally-activated glycoprotein 1; TXGP1; gp34; CD252 |
| Appearance | Colorless liquid |
| Formulation | 200 µg affinity purified human antibody in phosphate-buffered saline (PBS) containing 0.02% Proclin 300 |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Anti-OX40L (Oxelumab), Human IgG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TNFSF4 |
|---|---|
| Synonyms | TXGP1 |
| Function | Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. |
| Cellular Location | Membrane; Single-pass type II membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
OX40 is also known as CD134 is a member of the tumor necrosis factor receptor superfamily (TNFR). OX40 plays an important role in CD4+ and CD8+T-cells and B-cells response. Binding of OX40 to its ligand, OX40L provides co-stimulatory signal to effector T-cells without CD28 activation.
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