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Anti-β-Tubulin Antibody (1E1-E8-H4)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF |
|---|---|
| Primary Accession | P07437 |
| Reactivity | Human, Mouse, Rat, Monkey |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 1E1-E8-H4 |
| Calculated MW | 49671 Da |
| Gene ID | 203068 |
|---|---|
| Application & Usage | WB: COS7, LNCap, MCF7, C2C12, goat intestine, goat skeletal muscle, goat spleen, CHO-k1, COS7, C6, 3T3 and K562 cell lysates; IF: HeLa cells |
| Other Names | Tubulin beta chain, Tubulin beta-5 chain, TUBB, TUBB5 |
| Target/Specificity | β-Tubulin |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | In PBS (pH 7.4) containing with 0.02% sodium azide, 0.1mg/ml BSA and 50% glycerol |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Anti-β-Tubulin Antibody (1E1-E8-H4) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TUBB |
|---|---|
| Synonyms | TUBB5 |
| Function | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. |
| Cellular Location | Cytoplasm, cytoskeleton |
| Tissue Location | Ubiquitously expressed with highest levels in spleen, thymus and immature brain. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
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