CD10 Antibody
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC |
---|---|
Primary Accession | P08473 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Clone Names | 453F9G7 |
Calculated MW | 85514 Da |
Gene ID | 4311 |
---|---|
Gene Name | MME |
Other Names | Neprilysin, 3.4.24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN |
Dilution | IHC~~Ready-to-use |
Storage | Maintain refrigerated at 2-8°C |
Precautions | CD10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MME {ECO:0000303|PubMed:27588448, ECO:0000312|HGNC:HGNC:7154} |
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Synonyms | EPN |
Function | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573). |
Cellular Location | Cell membrane; Single-pass type II membrane protein |

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