TIA-1
Mouse Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P |
---|---|
Primary Accession | P31483 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 265E3G4 |
Calculated MW | 42963 Da |
Gene ID | 7072 |
---|---|
Gene Name | TIA1 |
Other Names | Cytotoxic granule associated RNA binding protein TIA1 {ECO:0000312|HGNC:HGNC:11802}, Nucleolysin TIA-1 isoform p40, RNA-binding protein TIA-1, T-cell-restricted intracellular antigen-1, TIA-1, p40-TIA-1, TIA1 |
Dilution | IHC-P~~Ready-to-use IHC~~Ready-to-use |
Storage | Maintain refrigerated at 2-8°C |
Precautions | TIA-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TIA1 |
---|---|
Function | Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. |
Cellular Location | Cytoplasm, Stress granule. Nucleus Note=Accumulates in cytoplasmic stress granules (SG) following cellular damage. |

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